Human · controlled/randomized1999
The Effect of Supplementation with a Cysteine Donor on Muscular Performance
Human study of a whey-based cysteine donor and muscular performance.
Open in PubMed →
Citable scientific resource
Evidence map: glutathione, Immunocal and cysteine-rich whey protein.
A tool to separate what has been studied in people from animal or laboratory work and from reviews. Every record in the verified core links directly to PubMed.
Difference explained
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Methods and scope
This resource combines two layers: the historical 92-publication collection already organized by Mas Glutation and a manually verified PubMed core. A literal PubMed search for “Immunocal” can include unrelated products sharing the same name, so the raw result count is not used as the number of nutritional-product studies.
19Verified PubMed core
11Human
5Animal
2In vitro
Methods review: 18 August 2026.
Verified PubMed core
Records checked individually and classified by design. Original titles are preserved for traceability.
Human · controlled/randomized2005
Effects of Cysteine Donor Supplementation on Exercise-Induced Bronchoconstriction
Human study of undenatured whey supplementation and exercise-induced bronchoconstriction.
Open in PubMed →Human · controlled/randomized2015
Effect of Cysteine-Rich Whey Protein (Immunocal®) Supplementation in Combination with Resistance Training on Muscle Strength and Lean Body Mass in Non-Frail Elderly Subjects: A Randomized, Double-Blind Controlled Study
Randomized double-blind study in non-frail older adults combined with resistance training.
Open in PubMed →Human · controlled/randomized2003
Improved Glutathione Status in Young Adult Patients with Cystic Fibrosis Supplemented with Whey Protein
Study in young adults with cystic fibrosis evaluating whey protein and glutathione status.
Open in PubMed →Human · controlled/randomized2002
Effects of Long-Term Supplementation with Whey Proteins on Plasma Glutathione Levels of HIV-Infected Patients
Double-blind study in advanced HIV infection focused on plasma glutathione and tolerability.
Open in PubMed →Human · open-label2001
Oral Supplementation with Whey Proteins Increases Plasma Glutathione Levels of HIV-Infected Patients
Clinical study of oral whey-protein supplementation in HIV infection and plasma glutathione.
Open in PubMed →Human · open-label2001
Nutritional Therapy of Chronic Hepatitis by Whey Protein (Non-Heated)
Open study in chronic hepatitis B or C using non-heated whey protein; findings differed between groups.
Open in PubMed →Human · pilot1995
The Use of a Whey Protein Concentrate in the Treatment of Patients with Metastatic Carcinoma: A Phase I-II Clinical Study
Very small phase I-II clinical study in metastatic carcinoma; it should be read as exploratory evidence.
Open in PubMed →Human · pilot2016
Biochemical and Clinical Effects of Whey Protein Supplementation in Parkinson's Disease: A Pilot Study
Pilot study in Parkinson’s disease examining whey-protein supplementation and biochemical/clinical variables.
Open in PubMed →Human · open-label2019
Cysteine/Cystine-Rich Undenatured Whey Protein Supplement in Patients' Pressure Ulcers Outcomes: An Open Label Study
Open-label study in patients with pressure ulcers; a clinical signal, not blinded evidence.
Open in PubMed →Human · controlled/randomized2021
Improving Antioxidant Capacity in Children With Autism: A Randomized, Double-Blind Controlled Study With Cysteine-Rich Whey Protein
Randomized double-blind controlled study of cysteine-rich whey protein in children with ASD; the authors call for confirmation.
Open in PubMed →Review2012
Immunocal® and Preservation of Glutathione as a Novel Neuroprotective Strategy for Degenerative Disorders of the Nervous System
Review of Immunocal, glutathione synthesis and proposed neuroprotective mechanisms; not a clinical trial.
Open in PubMed →Animal · preclinical2016
A Cystine-Rich Whey Supplement (Immunocal®) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
Preclinical research in a mouse model of ALS; it does not establish clinical efficacy in people.
Open in PubMed →Animal · preclinical2017
Cysteine-Rich Whey Protein Isolate (Immunocal®) Ameliorates Deficits in the GFAP.HMOX1 Mouse Model of Schizophrenia
Preclinical study in GFAP.HMOX1 transgenic mice; it should be read as mechanistic research.
Open in PubMed →In vitro · laboratory2017
A Cystine-Rich Whey Supplement (Immunocal®) Provides Neuroprotection from Diverse Oxidative Stress-Inducing Agents In Vitro by Preserving Cellular Glutathione
In-vitro work on oxidative stress and cellular glutathione; it is not clinical outcome evidence.
Open in PubMed →Animal · preclinical2018
The Cysteine-Rich Whey Protein Supplement, Immunocal®, Preserves Brain Glutathione and Improves Cognitive, Motor, and Histopathological Indices of Traumatic Brain Injury in a Mouse Model of Controlled Cortical Impact
Preclinical controlled-cortical-impact mouse model of traumatic brain injury.
Open in PubMed →Animal · preclinical2023
Immunocal® Limits Gliosis in Mouse Models of Repetitive Mild Traumatic Brain Injury
Preclinical mouse models of repetitive mild traumatic brain injury focused on gliosis/neuroinflammation.
Open in PubMed →Animal · preclinical2025
Immunocal®, a Cysteine-Rich Whey Protein, Rescues Reelin and Reduces Amyloid Plaque Burden in a Transgenic Amyloid-β Protein Precursor (hAβPPSweInd) Mouse Model of Alzheimer’s Disease
Preclinical transgenic mouse model of Alzheimer’s disease; this is not human clinical evidence.
Open in PubMed →In vitro · laboratory2000
Enhancing Effect of Patented Whey Protein Isolate (Immunocal®) on Cytotoxicity of Anticancer Drugs
In-vitro cancer-cell/drug study; it cannot establish a therapeutic effect in patients.
Open in PubMed →No matching records.
What this map can and cannot conclude
What this map can and cannot conclude
It can help identify study design, population/model and the original source.
It cannot turn preclinical results, pilot signals or reviews into therapeutic promises for an individual.
How to cite this resource
Mas Glutation (2026). Glutathione and Immunocal scientific evidence map. Review 2026-08-18.
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